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You have entered the IISP: Interactive Information System on Pathogenomics

 

If you would like to insert information about your research or research group, please click to the following link to download the form. After filling it out, please send back to m.karrasch@fz-juelich.de or g.gebreselassie@fz-juelich.de.

Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .

 

The following information is available and can be searched for:

  • researcher names
  • Institution of the respective researcher, city and country of his/her institution
  • Contact data of the researcher (address, phone, email)
  • Research topics and studied microorganisms of the researcher
  • Special techniques applied by the researcher
  • Potential cooperation topics suggested by the researcher

If you have any comments/questions or if you would like to add some information, please contact m.karrasch@fz-juelich.de

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Name: Prof. Dr. Ayala Serrano, Juan Alfonso
Address: Campus U.A.M. Cantoblance
Institution: Centro de Biologia molecular Severo Ochoa CSIC
 
City: Madrid Zip: ES-28049
Country: Spain Phone:
    Fax:
Email: jayala@cbm.uam.es
www:

 

Research Topics:
The objectives of our group are the analysis of the bacterial growth and cell division under diverse molecular approaches, and to study the mechanisms of resistance to the -lactam antibiotics, that have been developed by pathogens of clinical origin. Under this general scheme, we have developed two main aspects. One is the molecular characterization of the CTX-M -lactamases family, their mobilization mechanisms and the ancestral origin of the CTX-M-1 subfamily. And also the identification of PBPs and their role on the resistance mechanisms of anaerobic strains and Gram-negative enteric bacteria was analyzed. A new family of PBPs, belonging to the COG1680, with high homology with class C β-lactamases have been involved in morphogenesis and are going to be analyzed in a new project.

 

Organisms studied:
  • EPEC
  • ETEC
  • Pseudomonas aeruginosa
  • Salmonella typhimurium
  • Shigella sonnei

 

Special methods / technologies:
- Structural characterization of peptidoglycan and peptidoglycan biosynthesis precursors by HPLC - Characterization and quantification of penicillin-binding proteins. - In vivo analysis of DD-peptidases activities. - All general techniques for Genomics and Proteomics (RT-PCR, 2D-PAGE, MALDI-TOF MS, DNA sequencing)

 

Suggestions for potential research cooperations:
 
   
   
   
     
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