You have entered the IISP: Interactive Information System on Pathogenomics
If you would like to insert information about your research or research group, please click to the following link to download the form. After filling it out, please send back to email@example.com or firstname.lastname@example.org.
Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .
The following information is available and can be searched for:
- researcher names
- Institution of the respective researcher, city and country of his/her institution
- Contact data of the researcher (address, phone, email)
- Research topics and studied microorganisms of the researcher
- Special techniques applied by the researcher
- Potential cooperation topics suggested by the researcher
If you have any comments/questions or if you would like to add some information, please contact email@example.com
|Name:||Prof. Dr. Tomás Magańa, Juan|
|Address:||Avda. Diagonal 645|
|Institution:||Facultad de Biologia, Universidad de Barcelona|
|Molecular mechanisms of virulence in Gram-negative bacteria. Surface molecules/structures studied: lipopolysaccharide (O-antigen and LPS core). Biosynthesis, assembly, enzymology. Gram-negative bacteria, mainly animal pathogens Enterobacteria (mainly Klebsiella,Serratia and Plesiomonas) and Aeromonas (first priority) Other animal pathogens like Actinobacillus, Pasteurella, Vibrio, etc (second priority) capsule polysaccharide. Biosynthesis, assembly, linkage and enzymology outer-membrane proteins. Porins, siderophores, OmpX related proteins. flagella and pěli. Polar and lateral flagella , type IV pili, etc type III secretion and effector proteins delivered by this system In all these surface molecules/structures their role in pathogenesis when characterized by genomics and proteomics, and their potential use as vaccine candidtes Genetic regulation of these surface molecules/structures under infection conditions \'in vivo\'.|
|Special methods / technologies:|
|Mutants in frame by genetic recombination. \"in vivo\" studies and gene expression. Structural polysaccharide chemistry and enzymology. Immunoprotection studies in different animals with purified molecules/structures|
|Suggestions for potential research cooperations:|
|Use of candidate vaccines based in the LPS-core of different Gram-negative bacteria expressed in E. coli Our team is also open to new ideas that could consider our previous results obtained and published intersting for different projects and new in|