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You have entered the IISP: Interactive Information System on Pathogenomics

 

If you would like to insert information about your research or research group, please click to the following link to download the form. After filling it out, please send back to m.karrasch@fz-juelich.de or g.gebreselassie@fz-juelich.de.

Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .

 

The following information is available and can be searched for:

  • researcher names
  • Institution of the respective researcher, city and country of his/her institution
  • Contact data of the researcher (address, phone, email)
  • Research topics and studied microorganisms of the researcher
  • Special techniques applied by the researcher
  • Potential cooperation topics suggested by the researcher

If you have any comments/questions or if you would like to add some information, please contact m.karrasch@fz-juelich.de

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Name: Dr. Locht, Camille
Address: 1, rue du Prof. Calmette
Institution: Institut Pasteur INSERM U629
 
City: LILLE Zip: 59019
Country: France Phone:
    Fax:
Email: camille.locht@pasteur-lille.fr
www:

 

Research Topics:
Our laboratory is involved in the study of the pathogenesis of whooping cough and tuberculosis with the aim of developing new diagnostics, new drugs and new vaccines for these diseases. We tackle the problem both from the pathogen and the host points of view. We use molecular biology, biochemistry, proteomics, comparative genomics, transcriptomics, microbial physiology and immunology as tools to study host-pathogen interactions. We study the bacterial cell wall and important virulence factors, the genetic regulation of these factors at a whole genome-wide scale and, by way of comparative genomcis, the molecular epidemiology and phylogeny of Mycobacterium tuberculosis.

 

Organisms studied:
  • Bordetella pertussis
  • Mycobacterium tuberculosis

 

Special methods / technologies:
Protein purification, high-throughput targeted mutagenesis in B. pertussis, transcriptomics (DNA arrays) and proteomics (2D electrophoresis and mass spectrometry analysis) on Bordetella and Mycobacterium, NMR and X-ray crystallography on isolated proteins, animal models (nasal infection, aerosol and intravenous infection of mice)

 

Suggestions for potential research cooperations:
 
   
   
   
     
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