You have entered the IISP: Interactive Information System on Pathogenomics
If you would like to insert information about your research or research group, please click to the following link to download the form. After filling it out, please send back to firstname.lastname@example.org or email@example.com.
Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .
The following information is available and can be searched for:
- researcher names
- Institution of the respective researcher, city and country of his/her institution
- Contact data of the researcher (address, phone, email)
- Research topics and studied microorganisms of the researcher
- Special techniques applied by the researcher
- Potential cooperation topics suggested by the researcher
If you have any comments/questions or if you would like to add some information, please contact firstname.lastname@example.org
|Name:||Dr. Ferrandon, D.|
|Institution:||Equipe Fondation recherche Médicale, Institut de Biologie Moléculaire et Cellulaire|
|Country:||France||Phone:||03 88 41 70 17|
|Study of host-pathogen relationships using Drosophila melanogaster as a host. Our laboratory has focused on the study of the innate immune system of the fly, identifying and studying the components of the NF-kappaB signaling pathways that regulate the expression of effectors of the systemic immune response, including antimicrobial peptides (Rutschmann, Immunity 2000, Rutschmann Nature Immunology 2000). We have also discovered some of the Pattern Recognition Receptors that detect infections (Gottar, Nature 2002; Gobert, Science 2003) as well as a novel mode for sensing pathogens (Gottar, Cell 2006). We are currently investigating host-pathogen relationships from the vantage of both host and pathogen. We have developed an oral infection model with the Gram-negative entomopathogenic bacterium Serratia marcescens that rapidly escapes the digestive tract to enter the insect hemocoele. Whereas S. marcescens kills its host in less than 24 hours in a septic injury model, it takes 6 days to kill its host in the oral infection model. We have also a keen interest in understanding the pathogenesis mechanisms used by opportunistic fungi to kill their host.|
|Special methods / technologies:|
|Genetic analysis; histopathology of Drosophila melanogaster|
|Suggestions for potential research cooperations:|